Amputation due to PAD, particularly in patients with CLI, still a growing major concern
Despite progress in the treatment of peripheral artery disease (PAD) and critical limb ischemia (CLI), the rate of amputations and associated mortality remains high, particularly in CLI patients.
Low Quality of life
associated with CLI amputation
morbidity and mortality
on the healthcare system
CLI Mortality Rates
exceed those for every other form of occlusive cardiovascular disease, including symptomatic coronary artery disease (CAD), and reflect the systemic atherosclerotic burden associated with CLI.2